Colestyramine - Lipid modification

The PCN recommends, as per NICE CG71 (updated July 2016), that patients with Familial Hyperchosterolaemia (FH) with intolerance or contraindications to statins or ezetimibe, should be offered a referral to a specialist with expertise in FH for consideration for treatment with either a bile acid sequestrant (resin), nicotinic acid or a fibrate to reduce their LDL-C concentration. For those patients, bile acid sequestrants should be considered BLUE (without an information sheet) on the traffic light system Specialists to initiate treatment or make a recommendation for the primary care prescriber to initiate treatment.

See below for policy statement and further information