Joint Formulary & PAD

Prazosin hydrochloride - Benign prostatic hyperplasia

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Status 1

Non Formulary
Formulations :
  • Not Specified
Associated Icons :
BNF SPC
NFD1
Restrictions / Comments :

Documentation

  • No records returned.

PAD Profile

ChemicalSubstance :
Prazosin hydrochloride
Indication :
Benign prostatic hyperplasia
Group Name :
Keywords :
BPH, LUTS, urinary tract symptoms, urinary frequency, urinary incontinence
Brand Names Include :
Hypovase, Minipress
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
0

Other Indications

Below are listed other indications that Prazosin hydrochloride is used to treat.

Committee Recommendations (1)

Indoramin & Prazosin will be considered BLACK on traffic light system because these two drugs were not considered as part of the NICE clinical guideline. (CG97). Patients receiving these drugs on the NHS prior to this recommendation must be reviewed by their NHS consultant (or initiating clinician) but should be able to continue treatment until the patient and their NHS consultant (or initiating clinician) consider it appropriate to stop.

Where an alpha blocker is indicated, the PCN recommend one of the following as a 1st-line treatment option
- Tamsulosin (modified release) – GREEN (NOTE - prescribe as generic capsules)
- Doxazosin (immediate release) – GREEN (NOTE - XL / modified release preparations are considered BLACK)

Alfuzosin is more costly and is therefore not recommended as a 1st-line option. (NOTE - prescribe generically)

Terazosin is reserved for patients with hepatic or renal failure since no dose adjustment is required in these patient groups