Lansoprazole - Acid Suppression (Children)
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Status 1
Green (see narrative)
Formulations :
- Capsules
Formulary Status :
Associated Icons :
Restrictions / Comments :
Important
2nd line treatment option in children who are able to swallow capsules.
Some capsules are licensed to be opened and have their contents mixed with water, apple/tomato juice or sprinkled on soft food (e.g. yoghurt, apple puree)
Status 2
Green (see narrative)
Formulations :
- Oro-dispersible
Formulary Status :
Associated Icons :
Restrictions / Comments :
Important
2nd line treatment option in children unable to swallow omeprazole or lansoprazole capsules.
Oro-dispersible tablets disperse in the mouth to release gastro-resistant granules. Lansoprazole is NOT absorbed sublingually. The gastro-resistant granules must be swallowed for the medicine to be effective. The FasTabs® can also be administered in apple or orange juice.
Documentation
Guidelines (Local)
Patient resource
PAD Profile
ChemicalSubstance :
Lansoprazole
Indication :
Acid Suppression (Children)
Group Name :
Keywords :
reflux, GORD, gastro-oesophageal reflux disease, indigestion, PPI, Proton pump inhibitors, gastric acid, oesophagitis, gastro-resistant
Brand Names Include :
Zoton, Zoton FasTab
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
5
Traffic Light Entries :
2
Other Indications
Below are listed other indications that Lansoprazole is used to treat.
Other Drugs
Below are listed other drugs that are used to treat Acid Suppression (Children).
Committee Recommendations (1)
The Surrey Heartlands Integrated Care System Area Prescribing Committee (APC) has agreed an algorithm for prescribing PPIs in children (see below). Included medicines are:
Lansoprazole capsules are GREEN
- 2nd line treatment option in children who are able to swallow capsules
- For children who cannot swallow capsules, some capsules are licensed to be opened and have their contents mixed with water, apple/tomato juice or sprinkled on soft food (e.g. yoghurt, apple puree)
Lansoprazole orodispersible tablets are GREEN
- 2nd line treatment option in children unable to swallow omeprazole or lansoprazole capsules.
- Oro-dispersible tablets disperse in the mouth to release gastro-resistant granules. Lansoprazole is NOT absorbed sublingually. The gastro-resistant granules must be swallowed for the medicine to be effective. The FasTabs® can also be administered in apple or orange juice.
Omeprazole oral powder for suspension is BLUE (on recommendation of a specialist)
- ONLY for children under 10kg and/or with enteral feeding tubes (less than 8Fr) in place.
- Consider using the higher strength preparation, 20mg/5ml as proportion of sodium, potassium and preservatives per dose is less.
- Switch to alternative PPI as per algorithm when enteral feeding tube is removed or larger gauge used
Omeprazole dispersible tablets are GREEN
- 1st line treatment option in children unable to swallow omeprazole capsules.
- Mezzopram® brand is preferred due to the smaller granule sizes. If Mezzopram® is out of stock or unavailable Losec Mups® should be used as an alternative.
- Disperse the tablets in water, then mix with orange/apple/ pineapple juice, apple sauce or yoghurt
Omeprazole capsules are GREEN
- 1st line treatment option in children who are able to swallow capsules; OR
- For children who cannot swallow capsules, most capsules can be opened (licensed) and mixed with water or a slightly acidic fluid e.g. fruit juice, apple sauce
Esomeprazole granules are GREEN (advice updated Nov 24)
- Esomeprazole granules as branded product, Nexium® as an option in children and infants under the age of 1 with a NG tube >6 French (FR) in situ.(off-label use)
- Generic esomeprazole granules may be prescribed (3rd line) for infants and children under the age of 1 without an NG tube in situ where the parents or carers are having difficulties in giving part-dose using orodispersible tablets
Aclomep® powder is RED
- Only for use by Ashford & St Peters NICU
All other unlicensed oral PPI suspension prep