Joint Formulary & PAD

Clopidogrel - Stroke/TIA

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Status 1

Green
Formulations :
  • Tablets
Associated Icons :
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Clopidogrel
Indication :
Stroke/TIA
Group Name :
Keywords :
Ischaemic stroke, transient ischaemic attack
Brand Names Include :
Plavix
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
3

Other Indications

Below are listed other indications that Clopidogrel is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Stroke/TIA.

Committee Recommendations (4)

GENERIC clopidogrel has been considered by the PCN and has been assigned a GREEN traffic light status.

NOTE - the branded product, Plavix, was considered BLACK at the PCN in May 2017.
The network members were informed of recent advice from the Royal College of Physicians which recommends that the management of patients after stroke and a TIA should be the same, this is outside of license and national guidance from NICE. The Royal College of Physicians recommend Clopidogrel as a first line treatment option for patients following a stroke or TIA. NHS Surrey already have guidelines in place and are in line with these recommendations.
The committee discussed recommendations regarding the use of antiplatelets in stroke / TIA which were produced by SWL following NICE guidance issued in 2010. This had been conisdered and supported by the Surrey Stroke & Heart Network noting that the use of clopidogrel in TIAs is off license and outside of NICE recommendations.
Despite all of the generic clopidogrel preparations having a license for use in ACS, there are some restrictions applied to their Marketing Authorisations. However, the committee were satisfied that this restriction was merely a Patent protection issue and would support the prescribing and dispensing of generic clopidogrel for all of their licensed indications including in combination with aspirin for ACS