Joint Formulary & PAD

Isotretinoin - Acne

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Red
Formulations :
  • Capsules
Associated Icons :
SPC
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Isotretinoin
Indication :
Acne
Group Name :
Keywords :
PPP, pregnancy prevention programme, severe acne, nodular acne, conglobate acne
Brand Names Include :
Roaccutane
Important Information :

Important information and resources relating to the Pregnancy Prevention Programme and neuropsychiatric disorders are available on PAD (click drug name to see the PAD page for isotretinoin)

Latest Additions Date From :
15 Dec 2025
Latest Additions Date To :
31 Dec 2025
Guidelines :
Supporting Documents :
2

Committee Recommendations (2)

Important information and resources have been developed to help healthcare professionals, clinical leads and managers understand and implement the new safety measures for isotretinoin prescribing (including patient information resources).  

See links in the documentation section.

  The Area Prescribing Committee recommends the use of oral isotretinoin for the treatment of severe acne resistant to adequate courses of standard therapy with systemic antibacterials and topical therapy.


Isotretinoin will be considered RED with prescribing limited to or under the supervision of physicians with expertise in the use of systemic retinoids for severe acne and a full understanding of the risks and monitoring requirements.

For important information and resources related to Pregnancy Prevention Programme and neuropsychiatric disorders are available on PAD