Joint Formulary & PAD

Aripiprazole - Schizophrenia and other psychoses

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Status 1

Blue
Formulations :
  • Tablets
Associated Icons :
SPC
Restrictions / Comments :
Important
Preferred

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 

Status 2

Blue
Formulations :
  • Oro-dispersible tablets
Associated Icons :
R
SPC
Restrictions / Comments :
Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Reserve for patients who are unable to swallow tablets.

 

Status 3

Blue
Formulations :
  • Oral solution
Associated Icons :
R
SPC
Restrictions / Comments :
Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Oro-dispersible tablets are more cost effective than oral solution. Reserve oral solution for use in patients where the required dose is not available in an oro-dispersible form.

 

Status 4

Amber
Formulations :
  • Depot injection
Associated Icons :
SPC
Restrictions / Comments :
Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Shared-care arrangements are in place between SABP and Primay Care. For administration under the shared-care LCS when prescribed in Primary Care.

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

One monthly or two monthly injecton schedule available

  • Monthly injection – Deltoid or gluteal muscle
  • Injection every 2 months – Gluteal muscle only
Documents :
 
 

Status 5

Red
Formulations :
  • Depot injection
Associated Icons :
SPC
Restrictions / Comments :
Important

Where there is no LCS in place, the prescribing responsibility remains with SABP.

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

Documentation

  • No records returned.

PAD Profile

ChemicalSubstance :
Aripiprazole
Indication :
Schizophrenia and other psychoses
Group Name :
Keywords :
antipsychotics, depot antipsychotics, LAI, shared care
Brand Names Include :
Abilify, Abilify Maintena
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
1
Traffic Light Entries :
5

Other Indications

Below are listed other indications that Aripiprazole is used to treat.

Committee Recommendations (2)

The Surrey Heartlands Integated Care system Area Prescribing Committee recommends the administration of depot antipsychotic injections under an AMBER shared care agreement for practices that have signed up to the agreed locally commissioned service (LCS). The AMBER shared care includes a monthly injection schedule and a schedule for injections every 2 months.
 

Surrey Heartlands ICB have developed the LCS to enable stable patients with schizophrenia to be prescribed and administered these injections through their primary care prescriber (GP). 

If a practice has not signed up to the LCS the drug remains as RED status and prescriptions will be issued by the provider.

GENERIC Aripiprazole has been considered by the PCN and has been assigned a BLUE traffic light status.

NOTE - the branded product, Abilify, was considered BLACK at the PCN in May 2017.