Joint Formulary & PAD

Etanercept - Axial spondyloarthritis

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Status 1

Red
Formulations :
  • Subcutaneous injection (sc)
Associated Icons :
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Etanercept
Indication :
Axial spondyloarthritis
Group Name :
Keywords :
Biologic, anti-TNF, TNF-alpha, monoclonal antibody, cytokine modulator, nrAS, nr-AS, non-radiographic axial spondyloarthritis, ankylosing spondylitis
Brand Names Include :
Enbrel, Benepali, Erelzi
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
1

Other Indications

Below are listed other indications that Etanercept is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Axial spondyloarthritis.

Committee Recommendations (3)

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed the reviewed and updated axial spondyloarthritis pathway.

Treatment pathway is available on separate guidelines page.

The Medicines and Healthcare Products Regulatory Agency (MHRA) recommends to prescribe biological products by brand name to ensure that substitution of a biosimilar product does not occur when the medicine is dispensed by the pharmacist. Https://www/gov/uk/drug-safety-update/biosimilar-products

Primary care prescriber should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient's medication.

The PCN agreed the attached Spondyloarthritis biologic treatment pathway in line with TA383 which was published by NICE in February 2016. The PCN previously (March 2016) supported the branded prescribing of biosimilar etanercept (Benepali) to be used in all new patients for all indications where they have licensing authorisation in the UK. Switching to Benepali has been discussed locally with acute trusts and specialists.