Fludrocortisone acetate - Orthostatic hypotension

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Status 1

Blue

Formulations :

Tablets

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Associated Icons :

NICE

Off Label

SPC

Restrictions / Comments :

Important

Postural hypotension - off label use. Specialist team initiation and supply for at least 1 month before transfer of prescribing to primary care.

Documentation

Guidelines (National)

NICE NG71 Parkinsons-disease-in-adults

PAD Profile

ChemicalSubstance :

Fludrocortisone acetate

Indication :

Orthostatic hypotension

Group Name :

Keywords :

postural hypotension, low blood pressure, Parkinson's disease, diabetic neuropathy

Brand Names Include :

Important Information :

Latest Additions Date From :

Latest Additions Date To :

Guidelines :

Supporting Documents :

Other Indications

Below are listed other indications that Fludrocortisone acetate is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Orthostatic hypotension.

Committee Recommendations (1)

06 Jun 18 - Surrey & North West Sussex Area Prescribing Committee (formerly Prescribing Clinical Network)

Fludrocortisone, although unlicensed for this use, is recommended for the treament of postural hypotension in Parkinson's Disease. Refer to the SPC for clinical particulars including contraindications and interactions with other medicines.

Fludrocortisone should only be continued or initiated on request from a Parkinson's specialist and only after a review of existing medicines to address any potential pharmalogical causes for the hypotension (including antihypertensives, dopaminergics, anticholinergics, antidepressants).

Midodrine may be considered (2nd line after fludrocortisone) for the treatment of orthostatic hypotension in patients with Parkinson's Disease.
Again, see the Midodrine SPC for details of contraindications and monitoring requirements.