Joint Formulary & PAD

Doxylamine succinate/pyridoxine hydrochloride - Nausea and vomiting (pregnancy)

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Green (see narrative)
Formulations :
  • Gastro-resistant tablets
Associated Icons :
Restrictions / Comments :
Important
Not a preferred 1st-line option. Use only after failure of at least one established 1st-line treatment options

PAD Profile

ChemicalSubstance :
Doxylamine succinate/pyridoxine hydrochloride
Indication :
Nausea and vomiting (pregnancy)
Group Name :
Keywords :
morning sickness, nausea and vomiting in pregnancy
Brand Names Include :
Xonvea
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
1

Other Indications

Below are listed other indications that Doxylamine succinate/pyridoxine hydrochloride is used to treat.

  • No records returned.

Committee Recommendations (1)

The Surrey Heartlands APC approved doxylamine with pyridoxine for use in nausea and vomiting in pregnancy, acknowledging that the drug is licensed for this indication.

However, it was agreed that it should only be considered after a trial of a more established drug (off-label cyclizine, promethazine, prochlorperazine or chlorpromazine).

The Surrey Heartlands APC agreed a traffic light status and place in therapy for drugs used to treat nausea and vomiting in pregnancy.

Visit  the Guideline Profile page for a full list of these drugs and to access the CKS guidelines for nasea & vomiting and pregnancy and the BUMPS website (Best Use of Medicines in Pregnancy).