Joint Formulary & PAD

Progesterone - Threatened miscarriage

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Status 1

Red
Formulations :
  • Pessaries
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
Off Label
SPC
Restrictions / Comments :
Important

Cyclogest Off-label use. In women who experience bleeding in early pregnancy and those who have miscarried previously. Specialist only. 

 

Status 2

Red
Formulations :
  • Vaginal capsules
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
SPC
Restrictions / Comments :
Important

Prometrium - Soft Vaginal Capsules licensed indication as per SPC indicated for the prevention of miscarriage in women presenting with bleeding in the first trimester of pregnancy and have a history of recurrent miscarriages. Specialist Only

Documentation

  • No records returned.

PAD Profile

ChemicalSubstance :
Progesterone
Indication :
Threatened miscarriage
Group Name :
Keywords :
Brand Names Include :
Cyclogest, Prometrium
Important Information :
Latest Additions Date From :
17 Sep 2025
Latest Additions Date To :
24 Sep 2025
Guidelines :
Supporting Documents :
0
Traffic Light Entries :
2

Committee Recommendations (2)

17 Jul 25 - ASPH DTC

Prometrium agreed as a RED drug for it's licensed indication. An application to the APC for a change in traffic light status was discussed and to be explored by the specialist team. 

11 Feb 25 - Surrey Heartlands Medicines Optimisation Board (MOB)

This drug has been included on the joint formulary having been agreed by the DTC of at least one Surrey Heartlands Acute Trust.

See “Formulary Status” to identify where this drug has been agreed for use.

Other Indications

Below are listed other indications that Progesterone is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Threatened miscarriage.

  • No records returned.