Formulary Search
Search Results : Generalised Anxiety Disorder (GAD) (Duloxetine hydrochloride - Generalised Anxiety Disorder (GAD))
Show Icon and Status Keys
- Capsules
- Tablets
- Oral drops
- Oro-dispersible tablets
For use where ordinary tablets are not suitable.
- Tablets
- Capsules
- Oral solution
- Tablets
An SSRI is the usual 1st line treatment option.
An alternative SSRI or a SNRI is considered 2nd line.
Pregabalin is a 3rd-line option. Used as monotherapy in line with NICE guidance.
- Tablets
Off-label.
- Oral solution
Off-label.
100mg/5ml concentrate for oral solution - REQUIRES DILUTION
Reserve for patients who require a liquid formulation where an alternative SSRI liquid (citalopram drops, escitalopram drops or fluoxetine liquid) are not suitable.
Note – Dose must be diluted with 120mL of water, ginger ale, lemon/lime soda, lemonade or orange juice.
Dilution instructions are provided in the patient information leaflet: Sertraline 100mg/5ml concentrate for oral solution PIL
- Oral suspension
Off-label.
50mg/5ml oral suspension
Reserve for patients who require a liquid formulation only where:
- an alternative SSRI liquid (citalopram drops, escitalopram drops or fluoxetine liquid) are not suitable
- the patients is unable to manage the dilution of sertraline 100mg/5ml concentrate oral solution
- Modified release capsules
- Modified release tablets
In Primary Care, OptimiseRx will be used to recommend the most cost-effective formulation at the point of prescribing.
- Tablets
Only the modified-release formulations hold a license for anxiety disorders. The use of ordinary tablets is off-label.
- Tablets
Initiation and stabilisation by the Mental Health specialist team for a minimum of 3 months before any transfer of prescribing.
Not for routine initiation in new patients - risks of toxicity in overdose.
Use capsules where possible. Trazodone 50mg and 100mg tablets are disproportionately expensive and should not be prescribed if a capsule could be used.
- Capsules
Initiation and stabilisation by the Mental Health specialist team for a minimum of 3 months before any transfer of prescribing.
Not for routine initiation in new patients - risks of toxicity in overdose.
- Oral solution
Initiation and stabilisation by the Mental Health specialist team for a minimum of 3 months before any transfer of prescribing.
Not for routine initiation in new patients - risks of toxicity in overdose.
To prescribe as 50mg/5ml oral solution sugar free.
Note - the 100mg/5ml is very expensive and should not be prescribed.