Joint Formulary & PAD

Zoledronic acid - Osteoporosis

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PAD Profile

ChemicalSubstance :
Zoledronic acid
Indication :
Osteoporosis
Group Name :
Keywords :
Zoledronate
Brand Names Include :
Aclasta
Important Information :

5mg annual infusion

Latest Additions Date From :
10 Sep 2025
Latest Additions Date To :
Guidelines :
Supporting Documents :
4

Committee Recommendations (3)

IV Zoledronic acid for Osteoporosis – Information for GPs: Ashford and St. Peter's Hospitals NHS Foundation Trust (ASPH) and North West Surrey Place only.  Guidance has been produced to clarify for GPs the process used within ASPH to inform a patient’s GP that they have been initiated on IV zoledronic acid 

21 Nov 19 - Surrey Downs MOG

SDCCG LOCAL INFORMATION - Epsom & St Helier and the Surrey Downs CCG MOG have agreed an information sheet for GPs in relation to the assessment and management of fragility fracture patients on IV Zoledronic acid.

See SDCCG document below

Zoledronic acid (Aclasta) - To use only on the recommendation of a Consultant Rheumatologist or Geriatrician in patients with osteoporosis for whom a bisphosphonate is the most appropriate line of treatment and who are unsuitable for or unable to tolerate oral bisphosphonates for osteoporosis or who are unable to comply with them and for patients with fractures despite oral bisphosphonates. It should be administered only in a place with the required clinical governance systems in place (training of staff, IV administration protocols etc).

Other Indications

Below are listed other indications that Zoledronic acid is used to treat.