Pregabalin - Epilepsy
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Documentation
PAD Profile
Pregnancy risks - https://www.gov.uk/drug-safety-update/antiepileptic-drugs-in-pregnancy-updated-advice-following-comprehensive-safety-review
Pregabalin (Lyrica): findings of safety study on risks during pregnancy - GOV.UK
Respiratory depression - https://www.gov.uk/drug-safety-update/pregabalin-lyrica-reports-of-severe-respiratory-depression
Committee Recommendations (2)
From 1st April 2019 both pregabalin and gabapentin will be classified as a schedule 3 Controlled Drug. As such, the arrangements through which patients obtain these medicines will change.
The Surrey Medicines Commissioners Group have developed a patient template letter for local adaption - see below.
In addition, NHSE have produced a patient hand-out that is also available below
Please note the MHRA categorisations for each drug in the attached guidance (updated January 2014) and in the link below
Prescribers are reminded to undertake a proportionate risk benefit assessment prior to prescribing Pregabalin or Gabapentin for patients with a known or suspected propensity to misuse.
Other Indications
Below are listed other indications that Pregabalin is used to treat.
Other Drugs
Below are listed other drugs that are used to treat Epilepsy.
- Brivaracetam
- Cannabis (medicinal)
- Carbamazepine
- Cenobamate
- Clobazam
- Clonazepam
- Eslicarbazepine acetate
- Ethosuximide
- Gabapentin
- Lacosamide
- Lamotrigine
- Levetiracetam
- Oxcarbazepine
- Perampanel
- Phenobarbital
- Phenytoin
- Primidone
- Rufinamide
- Sodium valproate (NON childbearing potential)
- Sodium valproate (with childbearing potential)
- Stiripentol
- Sulthiame
- Tiagabine
- Topiramate
- Vigabatrin
- Zonisamide