Surrey Heartlands

Joint Formulary & PAD

Pregabalin - Pain (Neuropathic)

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Status 1

Green (see narrative)
Formulations :
  • Capsules
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
BNF SPC
CD
Restrictions / Comments :
Important
Gabapentin is preferred due to lower potential for misuse. Pregabalin capsules more cost effective than tablets
 

Status 2

Green (see narrative)
Formulations :
  • Oral solution
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
BNF SPC
CD
Restrictions / Comments :
 

Status 3

Non Formulary
Formulations :
  • Modified release tablets
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
BNF SPC
NFD2
Restrictions / Comments :

Pregabalin modified release tablets have not yet been assessed for formulary status and are not currently on the APC work-plan.

They have not yet been evaluated by the Surrey Heartlands ICS Area Prescribing Committee (APC).  As such, advice regarding safety, effectiveness (including cost-effectiveness) and its place in therapy is yet to be determined. 

Before prescribing this drug it is recommended that clinicians contact their Medicines Optimisation team to discuss possible alternatives/options.

The APC will consider recommending the prescribing of this treatment upon submission of a formal request with its associated evidence. Clinicians can contact syheartlandsicb.APC@nhs.net  if they wish to make a submission.

Documentation

Guidelines (Local)
Neuropathic Pain Guidelines for Primary Care - Oct 20
Guidelines (National)
NICE Clinical guideline [CG173] : Neuropathic pain in adults: pharmacological management in non-specialist settings
Safety Information
Pregabalin Safety Messages - GP Version - SABP Aug 2020 (updated Mar 2021)
Patient resource
Gabapentinoid Reduction - Patient_Information_Leaflet - Dec 2020
Information
Pregabalin and Gabapentin - Advice for prescribers on risk of misuse - December 2014

PAD Profile

ChemicalSubstance :
Pregabalin
Indication :
Pain (Neuropathic)
Group Name :
Keywords :
diabetic neuropathy, postherpetic neuralgia, PHN, neuropathic pain
Brand Names Include :
Lyrica
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
5
Traffic Light Entries :
3

Other Indications

Below are listed other indications that Pregabalin is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Pain (Neuropathic).

Committee Recommendations (1)

03 Feb 16 - Surrey & North West Sussex Area Prescribing Committee (formerly Prescribing Clinical Network)
Prescribers are reminded to undertake a proportionate risk benefit assessment prior to prescribing Pregabalin or Gabapentin for patients with a known or suspected propensity to misuse.

See Advice for Prescribers document below