Joint Formulary & PAD

Pizotifen - Migraine (prevention)

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Status 1

Green (see narrative)
Formulations :
  • Tablets
Associated Icons :
Restrictions / Comments :
Documents :
 

Documentation

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PAD Profile

ChemicalSubstance :
Pizotifen
Indication :
Migraine (prevention)
Group Name :
Keywords :
cluster headaches, migraine prevention, migraine prophylaxis
Brand Names Include :
Sanomigran
Important Information :
Review existing patients and consider alternative. Discontinuation of pizotifen requires gradual withdrawal.
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
1

Other Indications

Below are listed other indications that Pizotifen is used to treat.

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Committee Recommendations (3)

The Surrey Heartland Integrated Care System Area Prescribing Committee agreed a PAD narrative message for patients currently on treatment with pizotifen for migraine prophylaxis in primary care, as follows:

Long term use of pizotifen (like most migraine prophylactic medication) is rarely indicated and withdrawal should normally be attempted after 9 months. If, after 2-months of withdrawal, migraine frequency increases to warrant prophylactic medication again options to consider in discussion with the patient would be:
• Alternative prophylactic medication as per the Surrey Headache Pathway
• Re-start pizotifen only if there were no previous major side effects of low mood, weight gain and cognitive symptoms.

The Medicine Safety Committee has developed "Pizotifen safety advice" for healthcare professionals to consider when prescribing and monitoring patients on pizotifen

This drug has been agreed as appropriate for initiation in Primary Care and/or continued in Primary Care following a recommendation from specialists in other health care sectors. Following consideration by the PCN, it has been assigned a GREEN traffic light status