Surrey Heartlands

Joint Formulary & PAD

Topiramate - Migraine (prevention)

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Status 1

Green
Formulations :
  • Tablets
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
Guidelines BNF SPC
Restrictions / Comments :
 

Status 2

Green (see narrative)
Formulations :
  • Capsules
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
Guidelines BNF SPC
Restrictions / Comments :
Important
Capsules (Sprinkle) reserved for use in patients who cannot swallow tablets.
 

Status 3

Green (see narrative)
Formulations :
  • Oral suspension
Formulary Status :
Primary Care
ASPH
RSFT
SASH
SABP
Associated Icons :
Guidelines BNF SPC
Restrictions / Comments :
Important
Only use where patient cannot swallow tablets or capsules (sprinkle) are not suitable.

Documentation

Guidelines (Local)
Migraine Prevention - As described in CKS - July 2021
Guidelines (Local)
Adult Headache Referral and Management Guidance - Primary Care, Surrey Heartlands ICS - Feb 2023

PAD Profile

ChemicalSubstance :
Topiramate
Indication :
Migraine (prevention)
Group Name :
Keywords :
migraine prophylaxis, antimigraine, migraine prevention
Brand Names Include :
Topamax, Topamax sprinkle
Important Information :
Pregnancy Prevention Plan required for females of childbearing potential.
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Migraine (prevention)
Supporting Documents :
2
Traffic Light Entries :
3

Other Indications

Below are listed other indications that Topiramate is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Migraine (prevention).

Committee Recommendations (1)

07 Jul 21 - Surrey Heartlands Integrated Care System Area Prescribing Committee (APC)

The Surrey Heartlands Integrated Care System (ICS) Area Prescribing Committee has agreed a GREEN traffic light status for topiramate (prescribed generically), for migraine prophylaxis in line with NICE Clinical Knowledge Summaries (CKS). Note that topiramate is contraindicated in pregnancy.

Topiramate tablets
If indicated for women and girls of childbearing age ensure that a pregnancy prevention plan (PPP) is in place.


Topiramate capsules
Only use in patients who cannot swallow tablets and ensure that a PPP is in place for women and girls of childbearing age.


Topiramate liquid
Only use in patients who cannot swallow tablets or capsules and ensure that a PPP is in place for women and girls of childbearing age.

Information in CKS is available by following this link https://cks.nice.org.uk/topics/migraine/prescribing-information/drugs-for-the-prevention-of-migraine/