Joint Formulary & PAD

Valproic acid (NON childbearing potential) - Mania

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Status 1

Blue
Formulations :
  • Gastro-resistant tablets
Associated Icons :
SPC
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Valproic acid (NON childbearing potential)
Indication :
Mania
Group Name :
Keywords :
valproate semisodium, mania, manic episodes, bipolar disorder, psychotic disorders, mood disorders
Brand Names Include :
Belvo, Depakote, Syonell
Important Information :

Initiation and stabilisation by the mental health specialist team for at least 1 month before any request for transfer of prescribing responsbility to primary care.

See separate formulary entry for valproic acid in people WITH childbearing potential - important pregnancy-prevention requirement.

Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
2

Committee Recommendations (2)

Three infographics have been produced to clarify in which situations review by two specialists may be required for patients who are prescribed valproate:
•    for female patients under 55 years old
•    for male patients under 55 years old
•    for male and female patients 55 years and older

The Surrey Heartlands APC reviewed the Blue traffic light status for sodium valproate when used in patients with mental health disorders (mania, bipolar disorder, psychotics disorders, compulsive and agressive behaviours) and WITHOUT child-bearing potential.

The Blue status remains with the expectation that treatment will be initiated and stabilised by a specialist and patients will receive a minimum of 1 month supply from the specialist before transfer of care.

No supplementary information sheet is required

Other Indications

Below are listed other indications that Valproic acid (NON childbearing potential) is used to treat.