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Search Results : Constipation (Methylnaltrexone bromide - Constipation)
Records returned : 24 (on 29 May 2025 at 12:53:37).
Return to search results for ' Constipation '.
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Icon Key
NFD1
Non formulary
NFD2
Not assessed for formulary status. Apply to APC / DTC before use.
CD
Controlled drug. Prescribing and/or storage requirements may apply
R
Restrictions apply

Safety Alert

Unlicensed - no UK marketing license in place
Un
Off-label use. Not licensed for this indication.
NHSE
Treatment commissioned by NHS England
CDF
Cancer Drugs Fund
ICB
Treatment commissioned by the ICB
Link to the NICE website

Low carbon device
Status Key
Red
Specialist ONLY drugs - treatment initiated and continued by specialist clinicians
Amber
Prescribing initiated and stabilised by specialist but has potential to transfer to primary care under a formal shared care agreement
Green
GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing.
Green (see narrative)
GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing.
Please refer to the narrative on the Drug Profile page where additional information may be conveyed as to the place in therapy or restrictions for use that have been locally agreed.
Non Formulary
Not recommended for use in any health setting across the Surrey Heartlands Integrated Care System
Blue
Prescribing initiated and stabilised by specialist but has potential to transfer to primary care WITHOUT a formal shared care agreement. Please note that in some circumstances a specialist may recommend that prescribing can be started in primary care.
See narrative
See narrative - may be applied in instances where a traffic light status has not yet been agreed but an entry to the formulary has been made to clarify interim arrangements.
Drug
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Status
Restrictions/Comments
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- Not Specified
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- Not Specified
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Red
Formulations :
- Injection
Restrictions / Comments:
Important
For opioid-induced constipation in terminally ill patients when response to other laxatives is inadequate
RSCH Palliative Care Team only
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Green
Formulations :
- Enema
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Important
Allergy warning - contains peanut oil
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Green
Formulations :
- Suppositories
- Tablets
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Important
NOTE - 7.5mg suppositories are non-formulary.
Only the licensed 5mg and 10mg suppositories should be prescribed
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Non Formulary
Formulations :
- Not Specified
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Important
7.5mg suppositories are unlicensed and not approved for use in Surrey Heartlands.
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Indication :
Status :
Green
Formulations :
- Capsules
- Oral solution
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Indication :
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Green
Formulations :
- Enema
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Indication :
Status :
Green
Formulations :
- Suppositories
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Indication :
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Green
Formulations :
- Sachets (granules)
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Status :
Green
Formulations :
- Oral solution
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Indication :
Status :
Green
Formulations :
- Sachets (powder)
Restrictions / Comments:
Important
Prescribe as macrogol compound oral powder sachets. MHRA/CHM advice: Polyethylene glycol (PEG) laxatives and starch-based thickeners: potential interactive effect.
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Status :
Red
Formulations :
- Sachets (powder)
Restrictions / Comments:
Important
Moviprep / Plenvu - ADULTS only. Off-label use. MHRA/CHM advice: Polyethylene glycol (PEG) laxatives and starch-based thickeners: potential interactive effect.
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Green
Formulations :
- Oral suspension
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Status :
Green
Formulations :
- Tablets
Restrictions / Comments:
Important
Opioid-induced constipation.
Only after other laxatives have been unsuccessful.
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Indication :
Status :
Green
Formulations :
- Enema
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Important
Contraindicated in patients with CKD, dehydration and heart failure (among others).
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Indication :
Status :
Green
Formulations :
- Tablets
Restrictions / Comments:
Important
Only after a trial of at least 2 other classes of laxative at the highest recommended, tolerated doses. Consider stopping after 4 weeks if not effective.
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Status :
Green
Formulations :
- Liquid
- Tablets
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Indication :
Status :
Green
Formulations :
- Enema
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Links :
Indication :
Status :
Green
Formulations :
- Oral solution
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Indication :
Status :
Red
Formulations :
- Sachets (powder)
Restrictions / Comments:
Important
PICOLAX sachets - off-label use. ADULTS only at SASH. Adults and children at RSFT.
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Status :
Red
Formulations :
- Sachets (powder)
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Important
CITRAFLEET - ADULTS only. Off-label use
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Indication :
Status :
Green
Formulations :
- Sachets (granules)
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Indication :
Status :
Green (see narrative)
Formulations :
- Tablets
Restrictions / Comments:
Important
Opioid-induced constipation.
Only after other laxatives have been unsuccessful.
Formulary Status :
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