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A-Z of Drugs : A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A-Z of Drugs

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Search Results : Hypersalivation in adults (Trihexyphenidyl hydrochloride - Hypersalivation in adults)

Records returned : 12 (on 29 May 2025 at 12:52:41). Return to search results for ' Hypersalivation in adults '.

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Icon Key

NFD1

Non formulary

NFD2

Not assessed for formulary status. Apply to APC / DTC before use.

Controlled drug. Prescribing and/or storage requirements may apply

Restrictions apply

Safety Alert

Unlicensed - no UK marketing license in place

Off-label use. Not licensed for this indication.

NHSE

Treatment commissioned by NHS England

CDF

Cancer Drugs Fund

ICB

Treatment commissioned by the ICB

BlueTeq form to be completed

NICE

Link to the NICE website

Low carbon device

Status Key

Red

Specialist ONLY drugs - treatment initiated and continued by specialist clinicians

Amber

Prescribing initiated and stabilised by specialist but has potential to transfer to primary care under a formal shared care agreement

Green

GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing.

Green (see narrative)

GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing. Please refer to the narrative on the Drug Profile page where additional information may be conveyed as to the place in therapy or restrictions for use that have been locally agreed.

Non Formulary

Not recommended for use in any health setting across the Surrey Heartlands Integrated Care System

Blue

Prescribing initiated and stabilised by specialist but has potential to transfer to primary care WITHOUT a formal shared care agreement. Please note that in some circumstances a specialist may recommend that prescribing can be started in primary care.

See narrative

See narrative - may be applied in instances where a traffic light status has not yet been agreed but an entry to the formulary has been made to clarify interim arrangements.

Drug

Indication

Status

Restrictions/Comments

Formulary Status

Links

1. Trihexyphenidyl hydrochloride

Drug:

Trihexyphenidyl hydrochloride

Indication :

Hypersalivation in adults

Status :

Blue

Formulations :

Oral solution
Tablets

Restrictions / Comments:

Important

Off-label use. Transfer of prescribing responsibility to primary care after initiation and stabilisation of treatment - minimum of 1 month supply from the specialist team

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

2. Amitriptyline hydrochloride

Drug:

Amitriptyline hydrochloride

Indication :

Hypersalivation in adults

Status :

Green

Formulations :

Tablets

Restrictions / Comments:

Important

Off-label use. Lowest cost treatment option.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

3. Amitriptyline hydrochloride

Drug:

Amitriptyline hydrochloride

Indication :

Hypersalivation in adults

Status :

Green

Formulations :

Oral solution

Restrictions / Comments:

Important

Off-label use

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

4. Hyoscine hydrobromide

Drug:

Hyoscine hydrobromide

Indication :

Hypersalivation in adults

Status :

Green

Formulations :

Patches
Tablets

Restrictions / Comments:

Important

Off-label use.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

5. Hyoscine hydrobromide

Drug:

Hyoscine hydrobromide

Indication :

Hypersalivation in adults

Status :

Green (see narrative)

Formulations :

Oral solution
Oral suspension

Restrictions / Comments:

Important

100mcg per ml. Unlicensed formulation.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

6. Ipratropium bromide

Drug:

Ipratropium bromide

Indication :

Hypersalivation in adults

Status :

Green (see narrative)

Formulations :

Nasal spray
Sublingual spray

Restrictions / Comments:

Important

Nasal spray applied sublingually. Off-label use.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

7. Ipratropium bromide

Drug:

Ipratropium bromide

Indication :

Hypersalivation in adults

Status :

Green (see narrative)

Formulations :

Inhaler (Metered Dose)
Sublingual spray

Restrictions / Comments:

Important

Metered dose inhaler applied sublingually. Off-label use.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

8. Atropine sulfate

Drug:

Atropine sulfate

Indication :

Hypersalivation in adults

Status :

Blue

Formulations :

Eye drops
Sub-lingual drops

Restrictions / Comments:

Important

Off-label use. 1% Eye drops used sublingually. NOTE - the bottles (5ml / 10ml) are VERY expensive in primary care (>£150 per bottle) and should only be used where the unit dose Minims is not suitable and atropine is the required therapy. Primary Care may prescribe on request from the specialist team.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

9. Atropine sulfate

Drug:

Atropine sulfate

Indication :

Hypersalivation in adults

Status :

Blue

Formulations :

Eye drops (unit dose)
Sub-lingual drops

Restrictions / Comments:

Important

1% Minims eye drops used sublingually. Each unit dose can continue to be used for 24 hours after opening (multiple doses). One Minims unit per day. Off-label use. Primary Care may prescribe on request from the specialist team.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

10. Glycopyrronium bromide

Drug:

Glycopyrronium bromide

Indication :

Hypersalivation in adults

Status :

Blue

Formulations :

Tablets

Restrictions / Comments:

Important

Off-label use. Expensive treatment option - consider an alternative. Transfer of prescribing responsibility to primary care after initiation and stabilisation of treatment - minimum of 1 month supply from the specialist team.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :

SPC

11. Glycopyrronium bromide

Drug:

Glycopyrronium bromide

Indication :

Hypersalivation in adults

Status :

Blue

Formulations :

Oral solution

Restrictions / Comments:

Important

1mg/5ml oral solution (sugar free) off-label use. Transfer of prescribing responsibility to primary care after initiation and stabilisation of treatment - minimum of 1 month supply from the specialist team.

Formulary Status :

Primary Care

ASPH

RSFT

SASH

SABP

Links :