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Search Results : Pain (Ketoprofen - Pain )
Records returned : 62 (on 29 May 2025 at 13:28:35).
Return to search results for ' Pain '.
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NFD1
Non formulary
NFD2
Not assessed for formulary status. Apply to APC / DTC before use.
CD
Controlled drug. Prescribing and/or storage requirements may apply
R
Restrictions apply

Safety Alert

Unlicensed - no UK marketing license in place
Un
Off-label use. Not licensed for this indication.
NHSE
Treatment commissioned by NHS England
CDF
Cancer Drugs Fund
ICB
Treatment commissioned by the ICB
Link to the NICE website

Low carbon device
Status Key
Red
Specialist ONLY drugs - treatment initiated and continued by specialist clinicians
Amber
Prescribing initiated and stabilised by specialist but has potential to transfer to primary care under a formal shared care agreement
Green
GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing.
Green (see narrative)
GPs (or non-medical prescribers in primary care) are able to take full responsibility for initiation and continuation of prescribing.
Please refer to the narrative on the Drug Profile page where additional information may be conveyed as to the place in therapy or restrictions for use that have been locally agreed.
Non Formulary
Not recommended for use in any health setting across the Surrey Heartlands Integrated Care System
Blue
Prescribing initiated and stabilised by specialist but has potential to transfer to primary care WITHOUT a formal shared care agreement. Please note that in some circumstances a specialist may recommend that prescribing can be started in primary care.
See narrative
See narrative - may be applied in instances where a traffic light status has not yet been agreed but an entry to the formulary has been made to clarify interim arrangements.
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- Not Specified
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- Not Specified
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Green
Formulations :
- Tablets
Restrictions / Comments:
Important
Tablets can be dissolved in water (off-label)
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Indication :
Status :
Green (see narrative)
Formulations :
- Oral solution
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Important
Codeine phosphate oral solution 25mg/5ml.
Codeine linctus 15mg/5ml is ONLY licensed for cough.
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Indication :
Status :
Red
Formulations :
- Injection
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Green
Formulations :
- Oral solution
- Tablets
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Indication :
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Green (see narrative)
Formulations :
- Modified release tablets
Restrictions / Comments:
Important
Consider use if standard release tablets are not tolerated or compliance is an issue.
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Green
Formulations :
- Oral suspension
- Tablets
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Red
Formulations :
- Intravenous infusion
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Important
Restricted for patients where an oral NSAID is not suitable.
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Green
Formulations :
- Tablets
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Preferred
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Indication :
Status :
Green (see narrative)
Formulations :
- Effervescent tablets
- Soluble tablets
- Suppositories
Restrictions / Comments:
Important
Reserve for patients who cannot swallow solid dose forms.
Soluble / effervescent preparations have a high sodium content and more expensive than ordinary tablets.
Suppositories for use when oral route is not suitable
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Indication :
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Green (see narrative)
Formulations :
- Oral suspension
Restrictions / Comments:
Important
120mg/5ml and 250mg/5ml reserved for patients who cannot swallow solid dose forms or where sodium content of dispersible preparations is a problem.
Non-formulary: Paracetamol oral suspension 500mg/5ml. Much more expensive. Use a soluble formulation.
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Red
Formulations :
- Intravenous infusion
Restrictions / Comments:
Important
Prescribe in milligrams for doses <1g.
Review infusion prescriptions after 48-72 hours.
Note risk of overdose with IV paracetamol.
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Status :
Green (see narrative)
Formulations :
- Patches
Restrictions / Comments:
Important
Prescribe by brand. Care: available as 3-day, 4-day and 7-day patches.
Refer to Trust / Primary Care Pharmacy advice for locally preferred brands
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Blue
Formulations :
- Sublingual tablets
Restrictions / Comments:
Important
Use in patients unable to tolerate oral medications or where morphine is contra-indicated. If this formulation is indicated, prescribing may be initiated and stabilised by a specialist service but has the potential to transfer to primary care WITHOUT a formal shared care agreement. In some circumstances a specialist may recommend that prescribing can be started in primary care
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Indication :
Status :
Green (see narrative)
Formulations :
- Tablets
Restrictions / Comments:
Important
Fixed combinations are less preferable.
Low dose (8/500 co-codamol) not recommended.
Secondary Care - for A&E / discharge only.
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Indication :
Status :
Green (see narrative)
Formulations :
- Capsules
Restrictions / Comments:
Important
Capsules are more costly than tablets in primary care.
Fixed combinations are less preferable.
Low dose (8/500 co-codamol) not recommended.
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Indication :
Status :
Green (see narrative)
Formulations :
- Effervescent tablets
Restrictions / Comments:
Important
Fixed combinations are less preferable.
Low dose (8/500 co-codamol) not recommended.
Avoid effervescent formulations (high sodium content and more costly). Reserve for swallowing difficulties or patients with feeding tubes.
Secondary Care - for A&E / discharge only.
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Indication :
Status :
Green (see narrative)
Formulations :
- Tablets
Restrictions / Comments:
Important
Fixed combinations are less preferred. RSCH - prescribe as separate components - combination is non-formulary at RSCH.
The MHRA advises when prescribing dihydrocodeine with paracetamol, the tablet strength and dose must be clearly indicated
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Indication :
Status :
Green (see narrative)
Formulations :
- Immediate release tablets
- Oral solution
- Oro-dispersible
Restrictions / Comments:
Important
Orodispersible tablets are a cost-effective alternative to oral solution. Reserve oral solution and orodispersible tablets for patients in whom a solid dose form is not suitable.
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Indication :
Status :
Green (see narrative)
Formulations :
- Capsules (slow release)
- Granules (slow release)
- Tablets (slow release)
Restrictions / Comments:
Important
Prescribe modified-release preparations by brand - refer to local guidelines for preferred brands.
Zomorph capsules (12-hourly) can be opened for administration in patients unable to swallow the capsules.
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Indication :
Status :
Red
Formulations :
- Injection
- Solution for infusion
Restrictions / Comments:
Important
See separate listing for palliative care
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Indication :
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Non Formulary
Formulations :
- Suppositories
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Indication :
Status :
Green (see narrative)
Formulations :
- Tablets
Restrictions / Comments:
Important
Reserve for when alternatives are contraindicated or ineffective.
At RSFT - initiation by pain team only.
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Indication :
Status :
Green (see narrative)
Formulations :
- Capsules
- Oral solution
Restrictions / Comments:
Important
For patients unable to tolerate / poor response to morphine. Modified-release preparations to be prescribed by brand
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Indication :
Status :
Green (see narrative)
Formulations :
- Modified release tablets
Restrictions / Comments:
Important
For use in patients where morphine sulfate is not suitable / not tolerated.
Modified-release preparations to be prescribed by brand
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
Alternative for patients unable to tolerate / poor response to morphine.
Care with dose conversion.
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Indication :
Status :
Green (see narrative)
Formulations :
- Capsules
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Important
Consider use where maximum tolerated doses of codeine / dihydrocodeine are ineffective.
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Indication :
Status :
Green (see narrative)
Formulations :
- Modified release capsules
- Modified release tablets
Restrictions / Comments:
Important
Branded prescribing is recommended for modified release tramadol. Do not confuse 12 hourly and 24 hourly preparations.
Consider tramadol where maximum tolerated doses of codeine / dihydrocodeine are ineffective.
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Indication :
Status :
Green (see narrative)
Formulations :
- Soluble tablets
Restrictions / Comments:
Important
Reserved for patients unable to swallow solid dose forms or for administration via an enteral tube.
Consider use where maximum tolerated doses of codeine / dihydrocodeine are ineffective.
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Indication :
Status :
Green (see narrative)
Formulations :
- Oro-dispersible
Restrictions / Comments:
Important
Reserved for patients unable to swallow solid dose forms or for administration via an enteral tube.
Consider use where maximum tolerated doses of codeine / dihydrocodeine are ineffective.
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
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Indication :
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Non Formulary
Formulations :
- Oral solution
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Indication :
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Non Formulary
Formulations :
- Oral drops
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Blue
Formulations :
- Patches
Restrictions / Comments:
Important
Prescribe by brand in Primary Care. Not for use in opioid naïve patients. Limited place in therapy - on specialist advice only
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
See separate listing for use in assisted ventilation and anaesthesia
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Indication :
Status :
Red
Formulations :
- Injection
- Nasal spray
Restrictions / Comments:
Important
100mcg in 2ml injection used intranasally in paediatrics for painful procedures.
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Indication :
Status :
Non Formulary
Formulations :
- Buccal tablets
- Buccal/sublingual
- Lozenges
- Nasal spray
- Sublingual tablets
Restrictions / Comments:
Important
Immediate release fentanyl preparations are non-formulary for all pain indications EXCEPT for breakthrough pain in patients receiving opioid therapy for cancer pain.
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
See separate listings for palliative care and use in anaesthesia.
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
Limited stock - restrictions apply. Contact Pharmacy.
Safety alert for High Dose
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Indication :
Status :
Red
Formulations :
- Oral solution
Restrictions / Comments:
Important
On advice of Pain Team, Consultant Anaesthetist, Intensivist only.
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
On advice of Pain Team, Consultant Anaesthetist, Intensivist only.
Note - injection may be used sublingually or by buccal route (off-label use)
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Indication :
Status :
Red
Formulations :
- Intramuscular injection (IM)
Restrictions / Comments:
Important
Obstetric analgesia
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Indication :
Status :
Non Formulary
Formulations :
- Tablets
Restrictions / Comments:
Important
Tablets - Not for chronic or acute, non-malignant pain.
Intramuscular injection used in obstetric pain.
Formulary Status :
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Indication :
Status :
Red
Formulations :
- Inhalation
Restrictions / Comments:
Important
Acute, trauma pain.
RSFT - for
- use during removal of brachytherapy
- transperineal prostate biopsies
- pain management during diagnostic / therapeutic procedures
- pain management by the acute pain team for adult non-obstetric patients
Formulary Status :
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Indication :
Status :
Red
Formulations :
- Injection
Restrictions / Comments:
Important
Acute pain, including obstetric analgesia
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Tablets
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Red
Formulations :
- Not Specified
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Non Formulary
Restrictions / Comments:
Important
This status applies to the use of aspirin for pain.
Refer to separate formulary entries for caridology indications.
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Tablets
Restrictions / Comments:
Important
Fixed combinations are less preferred.
The MHRA advises when prescribing dihydrocodeine with paracetamol, the tablet strength and dose must be clearly indicated
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Tablets
Restrictions / Comments:
Important
Fixed combinations are less preferred.
The MHRA advises when prescribing dihydrocodeine with paracetamol, the tablet strength and dose must be clearly indicated
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Important
No longer licensed because of safety concerns, particularly toxicity in overdose.
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Important
Not for chronic or acute, non-malignant pain. See separate formulary entry for use in neuropathic pain.
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Important
Not for chronic or acute, non-malignant pain. See separate formulary entry for use in neuropathic pain
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Sublingual tablets
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Formulary Status :
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Indication :
Status :
Non Formulary
Formulations :
- Not Specified
Restrictions / Comments:
Formulary Status :
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