
Sacubitril/valsartan - Heart failure
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Status 1
Amber
Formulations :
- Tablets
Formulary Status :
Associated Icons :
Restrictions / Comments :
Status 2
Non Formulary
Formulations :
- Granules
Formulary Status :
Associated Icons :
Restrictions / Comments :
Important
Only licensed for use in children.
Documentation
Policy Statement
PAD Profile
ChemicalSubstance :
Sacubitril/valsartan
Indication :
Heart failure
Group Name :
Keywords :
Sacubitril, CHF, valsartan, neprilysin inhibitor, angiotensin receptor antagonist
Brand Names Include :
Entresto
Important Information :
Do not co-administer with an ACEi or ARB due to risk of angioedema.
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
5
Traffic Light Entries :
2
Other Indications
Below are listed other indications that Sacubitril/valsartan is used to treat.
Other Drugs
Below are listed other drugs that are used to treat Heart failure.
- Acetazolamide
- Bisoprolol fumarate
- Candesartan cilexetil
- Captopril
- Carvedilol
- Co-amilozide (Amiloride hydrochloride/hydrochlorot
- Dapagliflozin
- Digoxin
- Empagliflozin
- Enalapril maleate
- Enoximone
- Eplerenone
- Hydralazine hydrochloride
- Ivabradine
- Levosimendan
- Lisinopril
- Losartan potassium
- Metolazone
- Milrinone lactate
- Nebivolol
- Perindopril erbumine
- Prazosin hydrochloride
- Ramipril
- Spironolactone
- Valsartan
Committee Recommendations (1)
The PCN recommends Sacubitril/Valsartan (Entresto®) for treating symptomatic chronic heart failure with reduced ejection fraction in line with NICE guidance (TA388 – April 2016) and will be considered as AMBER on the traffic light system. CCGs in conjunction with local Acute Trusts will make local implementation plans as required