Joint Formulary & PAD

Empagliflozin - Heart failure

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PAD Profile

ChemicalSubstance :
Empagliflozin
Indication :
Heart failure
Group Name :
Keywords :
SGLT2s, SGLT2 inhibitors, sodium glucose co-transporter 2 inhibitors, chronic heart failure, CHF, HFrEF, reduced ejection fraction
Brand Names Include :
Jardiance
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
6

Other Indications

Below are listed other indications that Empagliflozin is used to treat.

Committee Recommendations (3)

The Medicines safety Committee has approved the 'Getting the most from your SGLT2 inhibitor (‘gliflozin’) medicine' PIL which can be adapted for use by services.

The Surrey Heartlands Integrated Care System Area Prescribing Committee (APC) approves empagliflozin:

  • as an option for treating adult chronic heart failure with reduced ejection fraction in addition to standard care (NICE TA773)
  • as an option for treating adult chronic heart failure with preserved or mildly reduced ejection fraction in addition to standard care (NICE TA929)

Treatment should be initiated or recommended by a heart failure specialist in patients with a formal diagnosis of heart failure as per NICE guideline on Chronic Heart Failure in adults

Heart Failure specialist defined as:

 • Cardiology consultant, specialist, or registrar

 • Heart failure specialist nurse

 • GP with a specialist interest in heart failure or GP cardiologist

 • General physician with heart failure expertise

 • Renal physician

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed a BLUE information sheet for empagliflozin and dapagliflozin for Adult Heart Failure with reduced ejection fraction (HFrEF) and a place in therapy document for these treatments in patients with Heart Failure.