Joint Formulary & PAD

Spironolactone - Heart failure

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Status 1

Green
Formulations :
  • Oral solution
  • Tablets
Associated Icons :
Restrictions / Comments :
Important
Preferred
Spironolactone is the preferred aldosterone antagonist for all stages of heart failure.

PAD Profile

ChemicalSubstance :
Spironolactone
Indication :
Heart failure
Group Name :
Keywords :
potassium sparing diuretics, aldosterone antagonists, hyperkalaemia
Brand Names Include :
Aldactone
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
1

Other Indications

Below are listed other indications that Spironolactone is used to treat.

Committee Recommendations (1)

GENERIC Spironolactone has been considered by the PCN and has been assigned a GREEN traffic light status.

NOTE - the branded product, Aldactone, was considered BLACK at the PCN in May 2017.

SAFETY NOTICE: In Feb 2016 the MHRA highlighted the risk of potentially fatal hyperkalaemia when spironolactone is used in combination with a renin-angiotensin drug in heart failure. The MCG approved the content of a guide which clarifies the monitoring requirements for patients on this combination - see guide below