Joint Formulary & PAD

Tofacitinib - Rheumatoid arthritis

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PAD Profile

ChemicalSubstance :
Tofacitinib
Indication :
Rheumatoid arthritis
Group Name :
Keywords :
RA, Biologic, NICE, immunosuppressant, DMARD, bDmard, Disease modulating, Rheumatology, cytokine modulator, Protein Kinase inhibitor, Jak inhibitor, Janus Kinase
Brand Names Include :
Xeljanz
Important Information :
Severe disease only
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
5

Other Indications

Below are listed other indications that Tofacitinib is used to treat.

Committee Recommendations (3)

The Surrey Heartlands Integrated Care System Area Prescribing Committee agreed the reviewed and updated rheumatoid arthritis pathway.

The Surrey Heartlands ICS Area Prescribing Committee have agreed an update of the Rheumatoid Arthritis High Cost DMARDs Drug Treatment Pathway. 

The pathway has been updated following guidance from the Regional Medicines Optimisation Committee in May 2020, in relation to the sequential use of biologic medicines. 

The PCN recommends tofactinib as a treatment option for the treatment of moderate to severe Rheumatoid Arthritis in line with NICE TA480.

Prescribing will be by hospital specialists only, in line with NICE TA480 using Blueteq initiation and continuation forms. Tofacitinib will be considered RED on the traffic light system.