Joint Formulary & PAD

Tofacitinib - Psoriatic arthritis

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Red
Formulations :
  • Tablets
Associated Icons :
BNF SPC
ICB
NICE
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Tofacitinib
Indication :
Psoriatic arthritis
Group Name :
Keywords :
RA, Biologic, NICE, immunosuppressant, DMARD, bDmard, Disease modulating, Rheumatology, cytokine modulator, Protein Kinase inhibitor, Jak inhibitor, Janus Kinase
Brand Names Include :
Xeljanz
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
4

Other Indications

Below are listed other indications that Tofacitinib is used to treat.

Committee Recommendations (3)

The Surrey Heartlands Integrated Care System Area Prescribing Committee agreed the reviewed and updated  Psoriatic arthritis high cost immunomodulator treatment pathway.

The Surrey Heartlands ICS Area Prescribing Committee have agreed an update of the Psoriatic Arthritis High Cost immunomodulator Drug Treatment Pathway. 

The pathway has been updated following guidance from the Regional Medicines Optimisation Committee in May 2020, in relation to the sequential use of biologic medicines. 

The Surrey & North West Sussex Area Prescribing Committee (APC) recommends tofacitinib as a treatment option in adult patients with active psoriatic arthritis after inadequate response to DMARDs in line with NICE TA 543 (October 2018)

Tofacitinib is a payment by results excluded medicine and initiation and subsequent monitoring of response will be by the rheumatology specialist service. Blueteq forms for initiation and continuation will be available for completion by specialist teams.

Tofacitinib will be considered as RED on the traffic light system

Primary care prescribers should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient’s medication.