Joint Formulary & PAD

Tofacitinib - Inflammatory bowel disease

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Red
Formulations :
  • Tablets
Associated Icons :
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Tofacitinib
Indication :
Inflammatory bowel disease
Group Name :
Keywords :
Ulcerative colitis, IBD, high cost immunomodulator, Sequential use of biologic medicines , JAK inhibitor, Janus Kinase, UC, Jakinib
Brand Names Include :
Xeljanz
Important Information :
Ulcerative colitis - adults only
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
2

Other Indications

Below are listed other indications that Tofacitinib is used to treat.

Committee Recommendations (2)

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed the reviewed and updated IBD immunomodulator pathway, which is to be found here - https://surreyccg.res-systems.net/PADFormularyV1Admin/Profile/Detail/7986 

The Surrey & North West Sussex Area Prescribing Committee (APC) recommends tofacitinib as a treatment option in adult patients with moderately to severely active ulcerative colitis in line with NICE TA 547 (November 2018)

Tofacitinib is a payment by results excluded medicine and initiation and subsequent monitoring of response will be by the gastroenterology specialist service. Blueteq forms for initiation and continuation will be available for completion by specialist teams.

Tofacitinib will be considered as RED on the traffic light system

Primary care prescribers should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient’s medication.