Joint Formulary & PAD

Ozanimod - Inflammatory bowel disease

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Red
Formulations :
  • Capsules
Associated Icons :
Restrictions / Comments :

PAD Profile

ChemicalSubstance :
Ozanimod
Indication :
Inflammatory bowel disease
Group Name :
Keywords :
Ulcerative colitis, UC, sphingosine 1-phosphate (S1P) receptor modulator, IBD,
Brand Names Include :
Zeposia
Important Information :
Ulcerative Colitis - adults only.
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
2

Other Indications

Below are listed other indications that Ozanimod is used to treat.

Committee Recommendations (2)

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed the reviewed and updated IBD immunomodulator pathway, which is to be found on the IBD guidelines page.

The Surrey Heartlands integrated care system Area Prescribing Committee (APC) approves ozanimod as recommended by NICE TA828 as an option for treating moderately to severely active ulcerative colitis in adults, only if:
•    conventional treatment cannot be tolerated or is not working well enough, and infliximab is not suitable, or
•    biological treatment cannot be tolerated or is not working well enough, and
•    the company provides it according to the commercial arrangement.

Ozanimod for this indication will be considered as RED on the traffic light system (treatment should be initiated and continued by specialist clinicians).
Primary care prescribers should be aware that their patient is receiving this medicine and ensure that this is recorded on the patient’s medication screen as a hospital-only drug in line with guidance on the PAD. This will also alert the prescriber to potential side effects and interactions with other medicines prescribed in primary care. It will also ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient’s medication