Joint Formulary & PAD

Upadacitinib - Inflammatory bowel disease

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PAD Profile

ChemicalSubstance :
Upadacitinib
Indication :
Inflammatory bowel disease
Group Name :
Keywords :
IBD, Ulcerative colitis, UC, Crohn's disease, high cost immunomodulator, Sequential use of biologic medicines , JAK inhibitor, Janus Kinase, Jakinib
Brand Names Include :
Rinvoq
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Supporting Documents :
5

Other Indications

Below are listed other indications that Upadacitinib is used to treat.

Committee Recommendations (3)

The Surrey Heartlands Integrated Care System Area Prescribing Committee has agreed the reviewed and updated IBD immunomodulator pathway, which is to be found here - https://surreyccg.res-systems.net/PADFormularyV1Admin/Profile/Detail/7986 

CROHN'S DISEASE

The Surrey Heartlands Integrated Care System Area Prescribing Committee recommends upadacitinib for previously treated moderately to severely active Crohn’s Disease in line with NICE TA905.

Upadacitinib will be given a RED traffic light status for this indication. Prescribing will be by hospital specialists only, in line with NICE TA905.

Primary care prescribers should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient's medication.

ULCERATIVE COLITIS

The Surrey Heartlands Integrated Care System Area Prescribing Committee recommends upadacitinib as a treatment option for the treatment of moderately to severely active Ulcerative Colitis in line with NICE TA856

Upadacitinib will be considered RED on the traffic light system. Prescribing will be by hospital specialists only, in line with NICE TA856.

Primary care prescribers should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient's medication.