Selegiline hydrochloride - Parkinson's disease
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Documentation
Guidelines (National)
PAD Profile
ChemicalSubstance :
Selegiline hydrochloride
Indication :
Parkinson's disease
Group Name :
Keywords :
Parkinsons disease, PD, monoamine-oxidase-B inhibitors, MAOB
Brand Names Include :
Eldepryl, Zelapar
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
1
Other Indications
Below are listed other indications that Selegiline hydrochloride is used to treat.
Other Drugs
Below are listed other drugs that are used to treat Parkinson's disease.
- Amantadine hydrochloride
- Apomorphine hydrochloride
- Bromocriptine
- Cabergoline
- Clonazepam
- Co-beneldopa
- Co-careldopa
- Entacapone
- Foslevodopa with foscarbidopa
- Levodopa with carbidopa and entacapone
- Melatonin
- Opicapone
- Orphenadrine hydrochloride
- Pergolide mesilate
- Pramipexole
- Procyclidine hydrochloride
- Rasagiline mesilate
- Ropinirole hydrochloride
- Rotigotine
- Safinamide
- Tolcapone
- Trihexyphenidyl hydrochloride
Committee Recommendations (1)
- Monoamine-oxidase-B inhibitors (rasagiline, selegiline), (or levodopa or dopamine agonists) are a first-line treatment option in the early stages of Parkinson's disease where motor symptoms do not impact quality of life.
- Monoamine-oxidase-B inhibitors are a choice of adjuvant treatment in patients who have developed dyskinesia or motor fluctuations despite optimal levodopa therapy.
Patients in whom Parkinson's is suspected should be referred quickly and untreated to a specialist.
Initiation may be carried out in Primary Care but only after recommendation by a specialist.
Modifications to therapy should only be carried out on specilaist advice.
Prescribers are reminded to prescribe generically and not by brand.