Joint Formulary & PAD

Melatonin - Sleep disorders in adults with neurodevelopmental disorders

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Status 1

Amber
Formulations :
  • Not Specified
Associated Icons :
SPC
Restrictions / Comments :
Important

This entry has not yet been reviewed for inclusion on the joint formulary. However, this information has been published due to the ongoing requirement for prescribers to access the shared care agreement and other resources that were in place prior to the launch of the joint formulary.

Please refer to the list of agreed formulations and former traffic light status available on the PAD page (accessed by clicking the drug name).

PAD Profile

ChemicalSubstance :
Melatonin
Indication :
Sleep disorders in adults with neurodevelopmental disorders
Group Name :
Keywords :
delayed sleep phase syndrome, DSPS, insomnia, ADHD, attention deficit hyperactivity disorder, persistent sleep disorder, sleep deprivation, autistic spectrum disorder, autism
Brand Names Include :
Circadin, Adaflex, Colonis
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
4

Other Indications

Below are listed other indications that Melatonin is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Sleep disorders in adults with neurodevelopmental disorders.

  • No records returned.

Committee Recommendations (1)

Unlicensed use.
The Area Prescribing Committee recommends the use of melatonin for sleep disorders in adults with neurodevelopmental disorders.

The recommended products are:

  • Melatonin 2mg MR tablets (prescribed generically) are recommended 1st line (off-label use)
  • Immediate release tablets (available in strengths of 1mg-5mg)
  • Crushed immediate release tablets (available in strengths of 1mg-5mg)  for patients unable to swallow tablets
  • Melatonin 1mg/ml oral solution sugar free (off-label use) may be considered, for example if the person has a feeding tube, or use of whole or crushed melatonin tablets is unsuitable due to significant difficulties with either the taste or texture. (Note - the liquid preparation, that is licensed in children and for jet lag, is also alcohol free)

Consideration should be given to switching existing melatonin patients to melatonin 2mg MR tablets, following review of treatment.

NON-FORMULARY 
- All other solid dose formulations of melatonin are not supported for use
- other liquid formulations
- Melatonin for use in jet lag
- The Slenyto® brand (1mg and 5 mg prolonged release tablets) has been assigned a BLACK status for all indications - see link for further information https://surreyccg.res-systems.net/PAD/Search/DrugConditionProfile/6243

Primary care prescribers should ensure that patient medication records include any medicine for which prescribing remains the responsibility of secondary or tertiary care. This will ensure that GP records, which are accessed by other healthcare providers, are a true and accurate reflection of the patient's medication


The use of melatonin in adult patients with other conditions has also been considered - please see links to "other conditions" at the top-right of this page