Joint Formulary & PAD

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A-Z of Drugs : A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A-Z of Drugs

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Search Results : Schizophrenia and other psychoses (Clozapine - Schizophrenia and other psychoses)

Records returned : 41 (on 04 Sep 2025 at 05:02:21). Return to search results for ' Schizophrenia and other psychoses '.

Show Icon and Status Keys

Drug
Indication
Status
Restrictions/Comments
Formulary Status
Links
Status :
Red
Formulations :
  • Oral suspension
  • Oro-dispersible tablets
  • Tablets
Restrictions / Comments:

Important

Treatment resistant schizophrenia.
NOTE: patient, prescriber and supplying pharmacy must be registered with the patient monitoring system. 

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

MHRA/CHM advice: Clozapine and other antipsychotics: monitoring blood concentrations for toxicity (August 2020)

MHRA/CHM advice: Clozapine: reminder of potentially fatal risk of intestinal obstruction, faecal impaction, and paralytic ileus (October 2017)

 
Links :
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

Second line treatment option in the management of schizophrenia once metabolic syndrome has been identified.

 
Links :
SPC
Status :
Blue
Formulations :
  • Tablets
Restrictions / Comments:

Important
Preferred

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Oro-dispersible tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Reserve for patients who are unable to swallow tablets.

 
Links :
R
SPC
Status :
Blue
Formulations :
  • Oral solution
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Oro-dispersible tablets are more cost effective than oral solution. Reserve oral solution for use in patients where the required dose is not available in an oro-dispersible form.

 
Links :
R
SPC
Status :
Amber
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Shared-care arrangements are in place between SABP and Primay Care. For administration under the shared-care LCS when prescribed in Primary Care.

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

One monthly or two monthly injecton schedule available

  • Monthly injection – Deltoid or gluteal muscle
  • Injection every 2 months – Gluteal muscle only
 
Links :
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Where there is no LCS in place, the prescribing responsibility remains with SABP.

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

 
Links :
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

Relief of acute symptoms of psychoses.

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Non Formulary
Formulations :
  • Injection
Restrictions / Comments:

Important

Relief of acute symptoms of psychoses.

 
Links :
NFD1
Status :
Blue
Formulations :
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Amber
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Flupenthixol decanoate - Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Shared-care arrangements are in place between SABP and Primary Care. Administration under the shared-care LCS when prescribed in Primary Care.

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

 
Links :
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Flupenthixol decanoate - where there is no LCS in place, the prescribing responsibility remains with SABP.

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

 
Links :
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

Off-label use.

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Capsules
Restrictions / Comments:

Important

Capsules are an unlicensed product.

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Amber
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Haloperidol decanoate - administration under the shared-care LCS when prescribed in Primary Care.

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

 
Links :
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Haloperidol decanoate - where there is no LCS in place, the prescribing responsibility remains with SABP.

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

 
Links :
SPC
Status :
Blue
Formulations :
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Oro-dispersible tablets
Restrictions / Comments:

Important

Reserve orodispersible tablets for patients with swallowing difficulties or administration via a PEG tube

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
R
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Olanzapine embonate - maintenance in schizophrenia.
Not suitable for  administration under the locally commissioned service (LCS).
Note 3 hour monitoring after dose .

 
Links :
SPC
Status :
Blue
Formulations :
  • Immediate release tablets
Restrictions / Comments:

Important
Preferred

 

 

Initiation and stabilisation by a SABP specialist for a minimum of 3 months before any request for transfer of prescribing responsibility.

 
Links :
Status :
Red
Formulations :
  • Modified release tablets
Restrictions / Comments:

Important

 

 

Modified release tablets are reserved for use when immediate release tablets are not suitable.

Modified release quetiapine MAY be continued in Primary Care (after a 3-month period of stabilisation by SABP) where the use of immediate release tablets would risk destabilising the patient.

 
Links :
R
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

For acute and chronic psychoses.

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
Status :
Red
Formulations :
  • Oro-dispersible tablets
Restrictions / Comments:

Important

For acute and chronic psychoses.

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Only for use where the liquid formulation is unsuitable e.g. for supervised administration to ensure compliance.

 
Links :
R
SPC
Status :
Non Formulary
Formulations :
  • Depot injection
Restrictions / Comments:

Important

For acute and chronic psychoses.

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

Only for continuation in existing patients.

 
Links :
NFD1
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Oral solution
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for at least 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Blue
Formulations :
  • Tablets
Restrictions / Comments:

Important

Initiation by a SABP specialist and stabilisation for a minimum of 3 months before any request to transfer prescribing responsibility.

 
Links :
SPC
Status :
Amber
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Zuclopenthixol decanoate - shared-care arrangements are in place between SABP and Primary Care. Administration under the LCS agreement once being prescribed in Primary Care.

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

 
Links :
SPC
Status :
Red
Formulations :
  • Oral drops
Restrictions / Comments:

Important

In-patient administration only (SABP).

 
Links :
SPC
Status :
Red
Formulations :
  • Intramuscular injection (IM)
Restrictions / Comments:

Important

Zuclopenthixol acetate is an intermediate-acting antipsychotic formulation which should only be used on in-patient units for the short-term management of acute psychotic episodes and mania. When prescribing intramuscular zuclopenthixol, check that the prescription is clear and unambiguous in order to ensure the intended treatment is dispensed and administered.

 
Links :
R
SPC
Status :
Amber
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Shared-care arrangements are in place between SABP and Primary Care. Administration under the shared-care LCS when prescribed in Primary Care.

See shared-care document below

Principles for shared care found here: https://surrey.res.services/PAD/Profile/NonClinicalProfile/9136

 
Links :
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Paliperidone palmitate - where there is no LCS in place, the prescribing responsibility remains with SABP.

Secondary Care may prescribe for in-patients (on the instruction of a SABP specialist) and prescribing continued by SABP after discharge.

 
Links :
SPC
Status :
Non Formulary
Formulations :
  • Modified release tablets
Restrictions / Comments:

 
Links :
NFD1
SPC
Status :
Red
Formulations :
  • Capsules
Restrictions / Comments:

Important

SABP only - prescribing flowchart available via SABP.

Patient must be on highly effective contraceptive

 
Links :
R
SPC
Status :
Red
Formulations :
  • Depot injection
Restrictions / Comments:

Important

Unlicensed drug.

 
Links :
Status :
Non Formulary
Formulations :
  • Not Specified
Restrictions / Comments:

 
Links :
SPC
Status :
Non Formulary
Formulations :
  • Not Specified
Restrictions / Comments:

Important

Treatment resistant psychosis.

 
Links :
NFD1
SPC
Status :
Non Formulary
Restrictions / Comments:

 
Links :
NFD1
Status :
Non Formulary
Restrictions / Comments:

 
Links :
NFD1
Status :
Non Formulary
Restrictions / Comments:

 
Links :
NFD1