Joint Formulary & PAD

Liraglutide - Diabetes Mellitus

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Status 1

Green (see narrative)
Formulations :
  • Subcutaneous injection (sc)
Associated Icons :
Restrictions / Comments :
Important
Preferred
Liraglutide is 1st-line for patients who wish to have a DAILY injection. Dulaglutide is the preferred WEEKLY injection.

PAD Profile

ChemicalSubstance :
Liraglutide
Indication :
Diabetes Mellitus
Group Name :
Antidiabetic drugs
Keywords :
GLP-1s, GLP1s, GLP 1s, glucagon like peptide-1, blood glucose lowering drugs, Type II
Brand Names Include :
Victoza, Diavic, Zegluxen, Liraglutide Biocon
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
3

Other Indications

Below are listed other indications that Liraglutide is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Diabetes Mellitus.

Committee Recommendations (2)

Liraglutide is 1st-line for patients who wish to have a daily GLP-1 injection.

Dulaglutide continues to be the preferred GLP-1 where weekly injection is indicated.

Semaglutide is an alternative option for weekly injection.

Lixisenatide is no longer a preferred treatment but remains an option.

Treatment with GLP-1s should be reviewed at 6 months. If there is no beneficial metabolic response (defined in NICE guidance), then stop treatment, and consider alternative treatment (usually insulin initiation) in line with NICE guidance

A PREFERRED GLP-1 RECEPTOR AGONIST: Widely used, dose adjustment not required in severe renal impairment and has randomised controlled trial data to show improved cardiovascular outcomes Treatment should be reviewed at 6 months. If there is no beneficial metabolic response (defined in NICE guidance), then stop treatment, and consider alternative treatment (usually insulin initiation) in line with NICE guidance