Joint Formulary & PAD

Dapagliflozin - Diabetes Mellitus

I agree that in using this database I understand that this platform only provides guidance on local prescribing policy and that all prescribing decisions are ultimately the responsibility of the clinician.

Status 1

Green (see narrative)
Formulations :
  • Tablets
Associated Icons :
Restrictions / Comments :
Important
Type 2 diabetes. Empagliflozin is the preferred SGLT-2 Dapagliflozin is not a preferred treatment option. Trusts restrict to diabetic team initiation only.
 

Status 2

Non Formulary
Formulations :
  • Tablets
Associated Icons :
Restrictions / Comments :
Important
Not licensed in Type 1 diabetes. Not to be initiated in new Type 1 patients. Shared care remains in place for existing patients only.

PAD Profile

ChemicalSubstance :
Dapagliflozin
Indication :
Diabetes Mellitus
Group Name :
Keywords :
SGLT2s, SGLT2 inhibitors, sodium glucose co-transporter 2 inhibitors, diabetic ketoacidosis, DKA
Brand Names Include :
Forxiga, Xigduo
Important Information :
Latest Additions Date From :
Latest Additions Date To :
Guidelines :
Supporting Documents :
12
Traffic Light Entries :
2

Other Indications

Below are listed other indications that Dapagliflozin is used to treat.

Other Drugs

Below are listed other drugs that are used to treat Diabetes Mellitus.

Committee Recommendations (3)

The Medicines safety Committee has approved the 'Getting the most from your SGLT2 inhibitor (‘gliflozin’) medicine' PIL which can be adapted for use by services.

INTERIM POSITION STATEMENT:
The Surrey Heartlands Integrated Care System Area Prescribing Committee have agreed the following statement for dapagliflozin with insulin for treating type 1 diabetes:

For existing patients: Continue with GP prescribing as AMBER status, with a view to developing an agreement with the specialists that treatment is reviewed at the patients next specialist diabetes review.  See risk minimisation materials below
 

For new patients: Do not initiate in new patients

Not a preferred treatment option in type 2 diabetes

See guidelines below and associated documentation for further information

The PCN noted that Dapagliflozin is a treatment option in NICE TA 288 & TA390